Download Clinicopathologic Principles for Veterinary Medicine by Wayne F. Robinson, Clive R. R. Huxtable PDF

By Wayne F. Robinson, Clive R. R. Huxtable

Written for veterinary undergraduates, this accomplished textual content explores the customarily obscured hyperlink among disorder on the cellphone and tissue point, and that encountered via the operating clinician. in accordance with a path taught via the editors, the ebook makes an attempt to strike a stability among the desires of the scholar and professional wisdom. every one bankruptcy explains styles of disorder specifically organs and relates them to either the pathophysiologic alterations and the outward visual appeal of the ailing animal.

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A further example of a type IV reaction is allergic contact dermatitis (see also Chapter 11). This condition arises as the result of the absorption into the epidermis of certain chemicals which have the ability to bind to epidermal proteins. Once bound to the carrier protein the chemical acts as a hapten and the fully immunogenic complex stimulates a cellmediated immune reaction. The chemicals that induce allergic contact dermatitis are usually relatively simple; they include such compounds as formaldehyde, picric acid, aniline dyes, plant resins, organophosphates and even salts of metals such as nickel, chromium and beryllium.

This refers to selective deficiency of one or more classes of immunoglobulin (B cell) and may be associated with variable T cell deficiency and infectious or autoimmune disease. Some patients may be clinically normal. a Fig. 18. Developmental pathways of the immune system and developmental blocks leading to immune failure. The defects are classified as (1) recticular dysgenesis, (2) severe combined immunodeficiency, (3) thymic aplasia, (4) agammaglobulinemia, (5) lymphokine deficiency, (6) deficiency in individual immunoglobulins, (7) neutrophil defects, (8) T suppressor defect (dysgammaglobulinemia).

Evaluation of circulating red cells In most circumstances the erythron is assessed relatively easily by sampling the peripheral blood and quantifying: - The hemoglobin concentration. - The percent of red cells in the blood sample (hematocrit). - Red cell numbers. - The number of immature red cells (reticulocytes). A qualitative appraisal of a thin film blood smear is also carried out, particularly noting the size and shape of red cells. Quantitative evaluation of red cells The most consistent value between species of animals is the hemoglobin concentration, which ranges between 100 and 160 grams/liter.

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