Download Cardiovascular Physiology (10th Edition) (Mosby's Physiology by Achilles J. Pappano, Withrow Gil Wier PDF

By Achilles J. Pappano, Withrow Gil Wier

Cardiovascular body structure provides a fantastic figuring out of ways the cardiovascular procedure features in either well-being and disorder. excellent on your systems-based curriculum, this identify within the Mosby body structure Monograph sequence explains how the most recent suggestions follow to real-life medical situations:

- Get transparent, actual, and up to the moment insurance of the body structure of the cardiovascular system.
- grasp the fabric simply with targets first and foremost of every bankruptcy; self-study questions, summaries, and keyword phrases and ideas; and a multiple-choice overview examination to assist prep for USMLEs.
- snatch the newest thoughts in vascular, molecular, and mobile biology as they follow to cardiovascular functionality, due to molecular commentaries in every one chapter.
- observe details to medical occasions simply by medical commentaries and highlighted medical vignettes throughout.

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Extra resources for Cardiovascular Physiology (10th Edition) (Mosby's Physiology Monograph)

Example text

CLINICAL BOX Most of the experimentally induced changes in transmembrane potential shown in Figure 2-18 also take place in patients with coronary artery disease. When blood flow to a region of the myocardium is diminished, the supply of oxygen and metabolic substrates delivered to the ischemic tissues is insufficient. The Na+,K+-ATPase in the membrane of the cardiac myocytes requires considerable metabolic energy to maintain the normal transmembrane exchanges of Na+ and K+. When blood flow is inadequate, the activity of the Na+,K+-ATPase is impaired, and the ischemic myocytes gain excess Na+ and lose K+ to the surrounding interstitial space.

The fiber bundle was stimulated at some distance from the impaled cell, and the stimulus artifact (St) appears as a biphasic spike to the left of the upstroke of the action potential. The time from this artifact to the beginning of phase 0 is inversely proportional to the conduction velocity. The horizontal lines near the peaks of the action potentials denote 0 mV. (From Myerburg RJ, Lazzara R. ) EXCITATION: THE CARDIAC ACTION POTENTIAL the upstrokes all diminished. As a consequence, the conduction velocity diminished progressively, as indicated by the distances from the stimulus artifacts to the upstrokes.

Release of acetylcholine from the cardiac parasympathetic nerves. 3 AUTOMATICITY: NATURAL EXCITATION OF THE HEART O B J E C T I V E S 1. Explain the basis of automaticity. 4. Describe the components of the electrocardiogram. 2. Describe the conduction of excitation through the heart. 5. Explain various cardiac rhythm disturbances. 3. Explain the basis of reentry. THE HEART GENERATES ITS OWN PACEMAKING ACTIVITY The nervous system controls various aspects of cardiac function, including the frequency at which the heart beats and the vigor of each contraction.

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