Download Behavioral Neurobiology of Aging by Kathleen M. Hayden, Kathleen A. Welsh-Bohmer (auth.), PDF

By Kathleen M. Hayden, Kathleen A. Welsh-Bohmer (auth.), Marie-Christine Pardon, Mark W. Bondi (eds.)

This quantity discusses the present country of analysis findings regarding fit mind getting older by way of integrating human scientific experiences and translational learn in animal types. a number of chapters supply a distinct review of winning getting older, age-related cognitive decline and its linked structural and practical mind adjustments, in addition to how those adjustments are motivated by means of reproductive getting older. Insights supplied via preclinical experiences in mouse versions and complex neuroimaging strategies in people also are presented.

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A. Depp et al. studies that examined genetic influences, and while these studies were not restricted to cognitive health as a phenotype, it is notable that the genes clustered into three groups (Glatt et al. , SIRT3). Although this body of literature is quite small, these fundamental physiological processes are linked, in the related literature, with indicators of cognitive decline. For example, a large body of literature indicates the associated links with the APOE SNP (Haan et al. 1999) and inflammation (McGeer and McGeer 2003) with Alzheimer’s Disease.

It is important to note that brain reserve and cognitive reserve are not competing or mutually exclusive models, rather these are two parallel processes that help to explain that there is more than one pathway to maintaining cognitive health in older age. 4 Wisdom In considering the phenotypes related to successful cognitive aging, memory and processing speed are prototypical cognitive domains that are associated with agerelated declines.

4 Wisdom In considering the phenotypes related to successful cognitive aging, memory and processing speed are prototypical cognitive domains that are associated with agerelated declines.

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